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Immune response monitoring by ELISPOT/FluoroSpot

Vaccines can be prophylactic and therapeutic for infectious diseases and cancer, depending on the formats of the antigens (virus, mRNA or DNA, recombinant protein, or synthesized peptide). The T- or B-cell-mediated antigen-specific response can be monitored by ELISpot or FluoroSpot to observe how cell frequencies have changed in response to a therapeutic intervention. We specialize in the isolation and cryopreservation of human peripheral blood mononuclear cells (PBMCs) from whole blood with high viability and function. We perform antigen-specific immune response assays with ELISpot/FluoroSpot to support your preclinical studies or clinical trials. We are able to provide the following services and customize them to your project needs:










Our laboratory continually develops new methods and customized approaches, from early screening through preclinical and clinical support. For additional information, please contact us at or call (858) 800-CURE (2873).

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  • Whole blood processing to cryopreserved PBMCs

  • T- and B-cell ELISpot/FluoroSpot tests

  • Assay optimization and standardization

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